Written by Thomas Rau (M.D.), Medical Director at Paracelsus Clinic and Josef Vizkelety (M.D.), Dentist at Paracelsus Clinic. www.paracelsus.com
An interdisciplinary approach of doctors & dentists at the Paracelsus Clinic
Each biological and therefore human system is susceptible to metals and heavy metals. They occur in various forms and accumulate in the human body. Metals and heavy metals oxidize and corrode, thereby forming metal ions and oxides which are toxic to our biological system, therefore the topic of metal and heavy metal poisoning is not to be underestimated. According to the American Agency for Toxic Substances and Disease Registry (ATSDR), based in Atlanta, USA, most of the metallic elements found in medicine and dentistry are a possible source of direct toxicity / poisoning. This can, in turn, alter neural cells / mitochondria and cell membranes, as well as promote permeability, dysregulations and the increase of the autoimmunity, which disrupts cellular processes¹ as well as promoting unspecific and specific immune responses.² Interestingly, more and more scientists and researchers are finding increased disruption in our neuro vegetative system, which is also known as “electrosensitivity”.³
The special metal mercury, which has a wide range of applications, can be found in products like vaccines, industrial additives, tattoos, seafood and amalgam fillings! Besides mercury, amalgam fillings mainly contain silver, tin and copper, all of which independently of each other can have a direct effect on our health, and in addition their adverse effects can be enhanced by mercury.
Mercury exists in three chemical structures:
- elemental mercury (vaccinations and thermometers)
- organic methyl / ethylmercury (amalgam fillings)
- inorganic mercury (fish & seafood and digestive tract)
Elemental and organic methyl / ethylmercury can pass undisturbed through the blood-brain barrier and the placenta while inorganic mercury can cause kidney toxicity. A unique property of amalgam fillings is the formation of super toxins / super bugs by combining mercury with oral anaerobic pathogenic microorganisms, which occur, for example, in dead teeth or root canal treated teeth.
All forms of mercury specifically bind sulphur containing compounds, such as cysteine, homocysteine, N-acetylcysteine, metallothionein, red blood cells and albumin.
There are thus many ways in which mercury can harm our body, for example as follows:
- Oxidative stress in cells of the intestinal tract, which in turn can cause leaky gut syndrome or to an increase in cytokine activity that can contribute to allergic reactions and the development of cancer, as well as an increase in antibiotic resistance
- Lung and bone disorders5 ,
- Skin disorders6 , cardiovascular disease7
- Renal disease, which inhibits the kidney from absorbing water and thus causing frequent urination8
- Neurological diseases such as ALS, MS, Parkinson’s disease and Alzheimer’s disease. When mercury is bound as methylmercury to the amino acid cysteine then it assumes similar functions as the amino acid methionine. This allows mercury to overcome the blood-brain barrier and contribute to direct neurotoxicity9
This list of harmful effects of mercury can go on and on, but what about the other metals, such as copper, cobalt, iron and chromium They can all oxidize fatty acids, also known as lipid peroxidation. Furthermore heavy metals such as arsenic, lead, mercury, and cadmium can displace essential minerals such as calcium, magnesium, and selenium, which can lead to poor calcium absorption, thyroid dysfunction, and stress-induced immunomodulation. Therefore it is all the more important to test metals and heavy metals and to eliminate them from our bodies.
- Metal stimulation test with DMPS (dimercaptopropanesulfonic acid) to bind metals / heavy metals, which can be excreted in the urine and thereby measured
- Hair mineral analysis: a measure of methyl / ethyl mercury and essential minerals
- Oligoscan: a laser applicator that can capture data from heavy metals and minerals
- Dark field analysis: a historically used analysis to assess characteristics of red and white blood cells
- The physical examination of the skin, mucous membrane and the nails
- LTT / Melissa Test for the measurement of potential metal allergies, including titanium hypersensitivity
After the severity of the metal and heavy metal toxicity has been determined, all dental metals are removed under special care and greatest possible protection and all dental replacements should be metal-free. Our holistic approach of dentistry would not be effective and complete if it would not be accompanied by the biological medicine according to Dr Thomas Rau, Medical Director and father of the Paracelsus Clinic. This biological medicine concept entails 3 main pillars of approach:
Removal of heavy metal sources
Dentistry: Amalgam fillings, metal crowns (usually made of palladium or gold, cobalt, chromium, nickel, copper and silver) and titanium implants are removed with special care. Special protective equipment such as oxygen, rubber dam, special suction devices, protective equipment and the application of Na-selenium and Na-thiosulfate are used under special care. All dental restorations should be done with metal-free materials, mostly ceramics.
Medicine: This could include the removal of titanium hip or knee prosthesis in case a patient develops an allergy to the metal
Detoxification, restoring digestive health, and milieu detoxification (blood plasma)
Supporting the liver by dietary changes including less dietary protein, fat and processed foods, reduced alcohol consumption, improvement of liver regulation and liver function. Improvement of the biochemical, coenzyme function and the metal bonding function.
Kidney support by improved kidney regulation and homeopathic support the kidney structure by drinking sufficient water.
Restoring digestive health
Removing food intolerances and supplying enough water and fibre, intake of Sanum products and acid-base balance regulation of the large intestine with lactic acid bacteria. In cases of leaky gut, the mucous membrane should be restored and a cellular detoxification initiated.
Adequate daily pure water consumption and regulation of the pH with alkaline powders and Sanum products. Adopting a healthy diet consuming a variety of vegetables, plant proteins and essential fats.
The above suggestions are general guidelines for detoxification. However, it is sometimes necessary to promote active removal of heavy metals with DMPS, DMSA, Fluminicil or EDTA. From our experience, we use DMPS to remove all metals, but nickel is removed best by EDTA.
Paracelsus Clinic Lustmühle under the supervision of Dr. Rau has specialised in body detoxification and has been helping our patients for more than 20 years. In addition, it is a necessary part of biological medicine that doctors and dentists work together to maximize the body’s efficiency and capacity to self-healing. Unfortunately, the environmental exposure of metals and heavy metals is increasing and we cannot avoid the exposer to this ever-growing danger. Our clinic recognizes this and has continued to extend and revise our detoxification program over the years to keep up with the advancement in this field and thus be successful as much as possible and to satisfy our patients.
1. Queen H. et al., Chronic mercury toxicity. Colorado Springs, Colorado: Queen and
Company Health Communications; 1988,
2. Goldman M et al., Druet P, Gleichmann E. TH2 cells in systemic autoimmunity:insights
from allogenic diseases and chemically- induced autoimmunity. Immunol Today 1991;
3. Weinberg et al., Mitochondrial bioenergetics during the initiation of mercuric chloride
induced renal injury. J Biol Chem 1982; 257:68–74.
4. Heo Y et al., Lead differentially modifies cytokine production in vitro and in vivo, Toxicol
Appl Pharmacol 1996; 138:149–57.
5. Nakagawa T et al., Effect of gold salts on the IgE immune response in mice. Ann
Allergy 1978; 40:272–5.
6. Rachmawati D et al., Toxicol In Vitro. 2015 Oct 9. pii: S0887-2333(15)00254-4. doi:
7. Biagini RE et al.,The diversity of reaginic immune responses to platinum and palladium
metallic salts. J Allergy Clin Immunol 1985; 76:794–802.
8. Bergman A et al.,Contact urticaria with anaphylactic reactions caused by occupational
exposure to iridium salt. Contact Dermatitis 1995; 35:14–7.
9. Mo?ller DR et al., Delayed anaphylactoid reaction in a worker exposed to chromium. J
Allergy Clin Immunol 1986; 77:451–6.
10. Mortazavi et al., Occupational exposure of dentists to electromagnetic fields produced
by magnetostrictive cavitrons alters the serum cortisol level.J Nat Sci Biol Med. 2012
11. Korraah et al., Induction of apoptosis and up-regulation of cellular proliferation in oral
leukoplakia cell lines inside electric field. Oral Surg Oral Med Oral Pathol Oral Radiol.
12. Santelmann et al., Electromagnetic fields and the pregnancies, Tidsskr Nor Laegeforen.
2012 May 15;132(9):1060-1.
13. Frick et al., Comparison perception of singular transcranial magnetic stimuli by
subjectively electrosensitive subjects and general population controls,
Bioelectromagnetics . (2005) 26:287-298
14. Di Pietro A et al., Biomonitoring of DNA damage in peripheral blood lymphocytes of
subjects with dental restorative fillings. Mutat Res 2008, 650:115-122.
15. Lorscheider FL et al., The dental amalgam mercury controversy–inorganic mercury and
the CNS; genetic linkage of mercury and antibiotic resistances in intestinal bacteria.
Toxicology 1995, 97:19-22.
16. Hahn LJ et al., Whole-body imaging of the distribution of mercury released from dental
fillings into monkey tissues. FASEB Journal 1990, 4:3256-3260.
17. Weidinger S et al., Body burden of mercury is associated with acute atopic eczema and
total IgE in children from southern Germany. J Allergy Clin Immunol 2004, 114:457-459.
18. Houston MC: The role of mercury and cadmium heavy metals in vascular disease,
hypertension, coronary heart disease, and myocardial infarction. Altern Ther Health Med
19. Mortada WI et al.,Mercury in dental restoration: is there a risk of nephrotoxicity? J
Nephrol 2002, 15:171-176.
20. Carpenter DO: Effects of metals on the nervous system of humans and animals. Int J
Occup Med Environ Health 2001, 14:209-218.
21. Gerhard I et al., Heavy metals and fertility. J Toxicol Environ Health. 1998, 54:593-611